RESEARCH STUDY “HEMATOPOIETIC PROPERTY OF THE ETHANOLIC EXTRACT OF Pleurotus ostreatus (OYSTER MUSHROOM) AMONG Oryctolagus cuniculus (MALE RABBITS)”

Escoba, C.A.; Duarte, K.S.L.; Desabille, K.E.L.; Estella, K.D

ABSTRACT

The study was conducted to determine the effectivity of Pleurotus ostreatus (oyster mushroom) ethanolic extract on the hematopoietic activity among Oryctolagus cuniculus. Pleurotus ostreatus (oyster mushroom) has been found to contain vitamins B1 (thiamin), B2 (riboflavin), B5 (niacin), B6 (pyridoxine) and B7 (biotin). The phytochemical screening of the mushroom extract revealed the presence of tannins, terpenoids, and glycosides.

A total of 20 Oryctolagus cuniculus (rabbits) were randomly assigned and employed into four groups. All showed a normal hematopoietic activity prior to testing.  There is statistical significance between treatments and time, and interaction of treatments and time; RBC (treatment=.034, time=.021, .interaction=.003); hematocrit = (treatment=.032, time=.024, interaction=004); hemoglobin (treatment=.034, time=.021, .interaction=.003).

Based on the gathered data and results, the researchers concluded that Pleurotus ostreatus (oyster mushroom) ethanolic extract has a potential hematopoietic effect among Oryctolagus cuniculus (rabbits).

RECOMMENDATIONS 

The researchers of this study yearn to improve the following:

1. That the future researchers might improve the methodology used by the proponents in this experimentation.

2. That there will be additional parameters to be studied upon aside from the red blood cell count, hematocrit and hemoglobin.

3. That there will be induction of any hematological abnormalities that could prove the effectiveness of Pleurotus ostreatus (oyster mushroom) and show that there is possibility that it could be used as an alternative treatment.