Journal Critique in Cardiovascular Risk Factors in
Elderly Normolipidemic Acute Myocardial Infarct Patients in India by CINDY ESCOBA, PEARL HARRIETTE RAMIREZ, CHARISH
PUENTENEGRA and GERARDINE CAÑETE under MR. JULIUS P. MARIO Faculty of the
College of Medical Technology of Southwestern University, Cebu City
The concern of
the uprising cases of myocardial infarction in patients had been tremendously
looked upon by the researchers to come up with valuable parameters in
determining myocardial infarction. Basically, they focused on the
cardiovascular risk factors which are mainly associated with the disease but
monitored with normolipidemic patients. With the emphasis of coronary artery
disease, various conditions have shown that lipid levels play a crucial role in
dealing cases with myocardial infarction due to free radical generation and
ischemia. Facts pertaining to the importance of observing high density
lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C)
in the introduction had been essentially explained as well as its mechanisms
involving oxidation by the antioxidant enzyme system. The objectives presented
are clear enough in accordance with the study and is in parallel with the use
of practical instrumentations conducive to the researchers’ benefit. The
abstract directly interpreted the significant results but with lesser
elucidation as to how relevant is determining the risk factors in elderly
normolipidemic AMI patients.
The
methodologies used in the study are well-established. The normolipidemic status
is judged by several diagnostic criteria. Although there is a thorough
selection of patients but there is no explanation stated as to why they come to
exclude several patients with diabetes mellitus or those with renal insufficiency.
There is specificity of the methods employed to every parameter but there
should have been an elaboration on the method’s principle why the researchers
are in favor to use it. With its wide-variety selection of tests, this study
can not be easily duplicated since all chemicals are of analytical grade and
are some are manufactured and obtained from other countries. The advancement of
technology in their country set an edge towards their study as quantitation is
concerned.
The results
obtained from the various methods are presented in a tabulated manner. The
tables are differentiated according to the patient’s status and other
biochemical parameters in patients. Moreover, the controls used provided a
solid foundation for the basis of their study. A further justification of the
legends has to be revised since some of it doesn’t correspond to the table
shown. The discussion points out the risk factors that can serve as markers for
detecting acute myocardial infarctions. The interpretation of results was
carefully evaluated by the researchers such then there were some redundancy
upon the antioxidants’ mechanism involving the disease. However,
recommendations are indicated as to evaluation of other inflammatory markers to
be given further consideration.
The topic and the
research framework are appropriate for the journal. It clearly relates to the
ideas discussed in the study. The abstract presented a brief yet an accurate
summary of the article that defines its purpose, methodology and the
discussion. The ideas are well-designated to its corresponding paragraphs in a
sense that it correlates to the results. The proponents have conveyed
understanding upon the readers as well as it exhibits a clearer picture of the
problem. In general, the presented research study is logical and significant.
